Frequently asked questions about AphthasolAphthasol oral paste 5% prescription medication for canker sores
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WHAT ARE CANKER SORES?
Canker sores, also called Aphthous ulcers, are painful sores that occur inside the mouth.  They can interfere with smiling and the pleasure of eating.  Canker sores are the most common ulcerative condition in the mouth.  About 20% of adults suffer from canker sores and about two thirds of canker sore suffers are women.  Once a person has initially experienced a canker sore the probability of their reoccurrence is high.  No specific cause for canker sores is known and they are NOT caused by a virus.  It is believed that canker sores develop when the body's own immune system attacks the cells lining the inside of the mouth. A number of factors are linked to the development of canker sores: stress, hormonal changes, trauma, nutritional deficiencies, allergies and immunological abnormalities.
WHAT DOES A CANKER SORE LOOK LIKE?
Canker Sore - Aphthasol speeds healingCanker sores look like small, whitish sores with red borders.   In its earliest stage, a canker sore will start with the formation of a reddish area, possibly it may be slightly elevated and often produces a tingling sensation.  This initial lesion progresses into an ulcer taking the following classic form:
  • A shallow individual ulcer which is round or oval in shape.
  • The ulcer will usually be no more than a 1/4 inch in diameter.
  • The center of the ulcer will be covered by a loosely attached white or grayish membrane.
  • The edges of the ulcer will be regular and surrounded by a halo.  The tissue adjacent to the canker sore will be healthy in appearance.
IN WHAT LOCATIONS DO CANKER SORES FORM?
Canker sores only form on the loose tissues of the mouth, those areas where the skin is not tightly bound to the underlying bone.  Canker sores  usually occur on the inside of the lips and cheeks, the floor of the mouth, the tongue, the soft palate, and the tonsillar areas. You may get only one sore in the mouth.  However, about 15 million patients suffer from "recurrent aphthous stomatitis," in which one experiences breakouts of multiple canker sores several times a month. 
WHAT ARE THE SYMPTOMS OF A CANKER SORE?
Canker sores, even a tiny sore the size of a pin head, can be very painful and make it difficult to eat, drink or even speak without discomfort.  Sometimes the spot where the sore will occur tingles or burns for a day or so before the sores actually appear.  Canker sores generally take about 10  - 14 days to disappear.
WHAT IS THE DIFFERENCE BETWEEN  CANKER SORES & COLD SORES?
Canker sores are small painful ulcerations occurring inside the mouth or gums.   They seem to be caused by stress, a physical nick or diet.  Unlike cold sores, canker sores are NOT contagious and NOT associated with the herpes simplex virus.  The main distinguishing feature is that cold sores erupt outside of the mouth on the lips, chin and sometimes under the nose, canker sores occur inside the mouth.
WHAT IS APHTHASOL & HOW DOES IT WORK?
Aphthasol (5% amlexanox in an adhesive oral paste) is a NEW prescription medication designed to provide relief and accelerate the healing of canker sores.   Aphthasol is the first FDA-approved prescription paste for treating Canker Sores in patients with normal immune systems.  Aphthasol is believed to work by inhibiting the formation and/or release of inflammatory mediators and it has the effect of limiting the extent of the progression of the ulceration of the canker sore.
 WHEN SHOULD I USE APHTHASOL?
APHTHASOL  is the only proven  treatment specific for canker sores that inhibits the progression of the ulceration. If you have ever been diagnosed by a physician with canker sores and suffer from recurrent outbreaks then Aphthasol may work for you.  Aphthasol paste should be applied as soon as possible after noticing the symptoms of an aphthous ulcer and should be used FOUR times daily, preferably following oral hygiene after breakfast, lunch, dinner, and at bedtime.  If you suffer from canker sores than be prepared and always have a tube on hand so you can use it at the first tingling signs of the onset of a canker sore.  Aphthasol will  help stop the progression of the ulceration and lessen the discomfort, pain, severity and duration of the canker sore resulting in the canker sores to disappear quicker!
WHAT ARE THE INDICATIONS FOR APHTHASOL?
Aphthasol is indicated for the treatment of canker sores in healthy adults with NORMAL immune systems.  Aphthasol is for topical use only for canker sores inside the mouth. Avoid contact with the eyes. 
HOW LONG DO I HAVE TO USE APHTHASOL?
Aphthasol should be used until the ulcer heals.  If significant healing or pain reduction has not occurred in 10 days, consult your dentist or physician!
 WHAT ARE THE  SIDE EFFECTS OF APHTHASOL?
There are very minimal side effects associated with Aphthasol topical application.    The most common adverse effects reported by 1 - 2 % of patients are transient pain, burning and/or stinging sensations at the site of application  No life-threatening symptoms have ever been reported.  Aphthasol paste is to be applied topically and used externally only.  It is NOT intended for internal use.
 WHO SHOULD NOT USE APHTHASOL?
WHAT ARE THE CONTRAINDICATIONS FOR APHTHASOL?
 CONTRAINDICATIONS:  In order to proceed to the medical consultation, you must go to the next page and read the contraindications and verify that you do not have any of the contraindications, you are not pregnant and are not breast feeding, and understand that if you have AIDS, or a suppressed immune system you must NOT use  Aphthasol (it's efficacy and safety have only been tested in healthy adults only)! Aphthasol  is CONTRAINDICATED in anyone with known hypersensitivity to the product or any of its components:   You must not use Aphthasol if you have a hypersensitivity to amlexanox :or any  of the inactive ingredients  benzyl alcohol, gelatin, glycerl monostearate, mineral oil, pectin, petrolatum or sodium carboxymethylcellulose.  Always inform your doctor before starting therapy.
Under NO circumstance is any  child under the age of 18, in anyone pregnant or breast-feeding, anyone with a compromised immune system or advanced HIV use Aphthasol  because Aphthasol has only been studied in healthy adults.
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