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Frequently asked questions about Denavir
WHAT ARE COLD SORES?
Cold sores, also known as fever blisters, are liquid-filled blisters that erupt around the lips and sometimes spread to the nose and chin.  One out of every 4 adults will develop a cold sore at some point in their adult life, and 80% to 90% of adults carry the Herpes Simplex I Virus responsible for cold sores. (This is NOT the same as herpes simplex II that causes genital herpes.) Once infected with the cold sore virus it stays dormant in the body and periodically  erupts as cold sores often related to stress, sun exposure, the flu etc.  Cold sores are extremely contagious and the herpes simplex I virus spreads by direct skin-to-skin contact. A  person may shed virus in the saliva even when cold sores are not present.
WHAT IS THE DIFFERENCE BETWEEN  COLD SORES & CANKER SORES?
Canker sores are small painful ulcerations occurring inside the mouth or gums.   They seem to be caused by stress, a physical nick or diet.  Unlike cold sores, canker sores are NOT contagious.  The main distinguishing feature is that cold sores erupt outside of the mouth on the lips, chin and sometimes under the nose, canker sores occur inside the mouth.   Since a canker sore inside the mouth is not associated with the herpes simplex virus, Denavir is NOT indicated!
WHAT DOES A COLD SORE LOOK LIKE?
A cold sore frequently starts as an irregular shaped blister on the lips and blisters can spread to the chin and under the nose area.  It quickly loses its top and becomes a shallow ulcer which often crusts on top.   Most often a fever, sunburn or stress may provoke an outbreak of cold sores.  Cold sores can be painful and severe cases can even leave scarring.  Many people who suffer from recurring cold sores feel a tingling or burning sensation a day before the cold sore erupts.  Cold sores can not be prevented but now for the first time ever there is a FDA approved treatment for recurrent cold sores, Denavir.
WHAT IS DENAVIR  & HOW DOES IT WORK?
DENAVIR (penciclovir cream 1 %) is  a medical breakthrough.  It is the first and only prescription medicine for recurrent cold sores in healthy adults  ever approved by the FDA.   In the largest ever clinical study, Denavir was proven to heal cold sore and shorten their duration by more than half the time and it helps relieve the symptoms of cold sores.   Denavir is an anti-viral medicine that penetrates the skin and blocks the viral DNA synthesis of the virus that causes cold sores.
WILL DENAVIR WORK FOR ME? WHEN SHOULD I USE DENAVIR ?
DENAVIR  is the only proven  treatment for recurrent cold sores. If you have ever been diagnosed by a physician with cold sores and suffer from recurrent outbreaks then DENAVIR may work for you.   Denavir is a smooth non greasy cream and comes in a small tube (small enough to fit in your pocket or purse).   When you feel the first signs of tingling prior to the onset of a cold sore or even if you already have a blister, you should apply Denavir to the area every 2 hours from the time you wake up until you go to sleep for 4 days. Denavir cream dries clear, it has no medicine taste and once you apply it it's hardly noticeable at all.  If you suffer from cold sores than be prepared and always have a tube on hand so you can use it at the first tingling sings of the onset of a cold sore.  Denavir will lessen the discomfort, pain, severity and duration of the cold sores and help the cold sores to disappear quicker!
WHAT ARE THE INDICATIONS FOR DENAVIR?
Denavir is indicated for the treatment of recurrent cold sores in healthy adults.  Denavir should only be used on cold sores on the lips and face.   It should not be used on mucous membranes, it should not be used inside the mouth, it should NEVER be used for genital herpes.  Avoid contact with the eyes because it can cause irritation. 
WHAT IF I MISS A DOSE?
If you miss  a dose, apply Denavir as soon as possible.   But do NOT double dose   Also do NOT exceed the recommended dose or frequency of application. 
HOW LONG DO I HAVE TO TAKE DENAVIR?
Over 80% to 90% of adults carry the cold sore virus and at least 1 in 4 will suffer from cold sores during their  life.   If you suffer from recurrent cold sores, you should always have a tube of Denavir on hand available when you feel the first onset of a cold sore.  You use the Denavir cream for 4 consecutive days for each outbreak that you experience. 
WHEN TAKING DENAVIR  CAN I STILL SPREAD THE VIRUS?
Yes!  There is no cure for cold sores and once you have the herpes simplex I virus in your body you are always a carrier.  You are extremely contagious during an outbreak of cold sores and Denavir  DOES NOT alter the contagious nature of the active cold sore, but it does hasten the healing of the cold sore!    Once you have herpes simplex I, even if you don't have active outbreaks  of cold sores  you are always potentially contagious and could be shedding virus in your saliva. But when you have cold sore lesions you must avoid kissing and direct contact because at this time you are especially contagious.
 WHAT ARE THE  SIDE EFFECTS OF DENAVIR?
There are very minimal side effects associated with Denavir cream topical application.   A few people experience headaches (about 5 %, slightly more than those receiving a placebo non-active cream) .   A less common side effect is a mild redness of skin (due to blood vessel dilation) where the cream was applied ( in less than 2% of patients).   No life-threatening symptoms have ever been reported.  Denavir cream is to be applied topically and used externally only.  It is NOT intended for internal use.  In case of accidental consumption of cream call 911 for emergency help or your local poison control center.
 WHO SHOULD NOT TAKE DENAVIR?
WHAT ARE THE CONTRAINDICATIONS FOR DENAVIR?
 CONTRAINDICATIONS:  In order to proceed to the medical consultation, you must go to the next page and read the contraindications and verify that you do not have any of the contraindications, you are not pregnant and are not breast feeding, and understand that if you have AIDS, a suppressed immune system, a bone marrow or kidney transplant, any organ transplant or kidney disease you must NOT use  Denavir (it's efficacy and safety have only been tested in healthy adults only)! Denavir is CONTRAINDICATED in anyone with known hypersensitivity to the product or any of its components:   You must not take Denavir if you have a hypersensitivity to penciclovir of famciclovir or any  of the inactive ingredients: cetomacrogol 1000 BP, cetostearyl alcohol, mineral oil, propylene glyclol, purified water and white petrolatum.   Always inform your doctor before starting therapy.
Under NO circumstance is any  child under the age of 18, in anyone pregnant or breast-feeding, anyone with an organ transplant, kidney disease or advanced HIV to take Denavir because Denavir has only been studied in healthy adults.
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